Cell Line Lysates
![ABclonal Technology [KO Validated] LAMP2 Rabbit pAb](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000106765.jpg-250.jpg)
ABclonal Technology [KO Validated] LAMP2 Rabbit pAb
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins.
ABclonal Technology PTPN1 Rabbit pAb
The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which catalyzes the hydrolysis of phosphate monoesters on tyrosine residues. PTPs are key signaling molecules that regulate cellular processes such as growth, differentiation, the cell cycle, and oncogenic transformation. This PTP acts as a negative regulator of insulin signaling by dephosphorylating the insulin receptor kinase. It also dephosphorylates epidermal growth factor receptor kinase, JAK2, and TYK2 kinases, implicating it in cell growth control and responses to interferon. Two transcript variants encoding different isoforms have been identified for this gene.
American Research Products Inc Mouse Macrophage scaVenger rec
Mouse Macrophage scaVenger receptor types I and II (MSR1) ELISA kit from CUSABIO Detection Range 0 156 ng/mL-10 ng/mL Sensitivity 0 039 ng/mL Sample serum plasma tissue homogenates Method Sandwich
World Precision Instrument Liquid Waveguide Capillary Cell, 500 cm pathlength
UV/VIS/NIR absorbance spectroscopy is governed by Beer’s Law, where the absorbance signal is proportional to chemical concentration, light path length and the compound’s specific molar absorption coefficient. Typical optical pathlengths of cuvettes and flow cells are between 0.2cm and 10 cm. Longer pathlengths are difficult to achieve due to mechanical constraints. Liquid Waveguide Capillary Cells (LWCCs) fill this gap. LWCCs are fiber optic flow cells that combine an increased optical pathlength (10–500 cm) with small sample volumes ranging from 2.4 µL to about 3mL. Compared with a standard 1cm cell, a 1 mAU signal is enhanced one hundred fold with a 100 cm flowcell to 100 mAU, using WPI’s patented aqueous waveguide technology.*
They can be connected via optical fibers to a spectrophotometer with fiber optic capabilities.
Biolegend Alexa FluorR 488 anti-RBFOX3 N
Alexa Fluor 488 anti-RBFOX3 (NeuN) [W18230A]; Isotype: Rat IgG2a, κ; Reactivity: Human, Mouse; Apps: IHC-F, IHC-P; Size: 100 μg
ABclonal Technology CCR7 Rabbit pAb
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants.
ABclonal Technology ARRB2 Rabbit pAb
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Cayman Chemical MethylspInazarIn 2.5mg
A bacterial metabolite and COMT inhibitor (IC50 = 0.8 μg/ml); selective for COMT over tyrosine hydroxylase, DOPA decarboxylase, and dopamine-β-hydroxylase at 100 μg/ml; decreases blood pressure in spontaneously hypertensive rats at 50 mg/kg
Bioss KD-Validated DYNLL1 Rabbit Rec
Dynein Light Chain LC8-Type 1 Primary Antibody Unconjugated Public Immunogen Range 2450-2511/2511 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB FCM Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
ABclonal Technology Bcl10 Rabbit pAb
This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants.
Bioss KD-Validated Catenin alpha 1 R
Catenin Alpha 1 Primary Antibody Unconjugated Public Immunogen Range 1-65/906 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
Cytoskeleton, Inc. BlastR Rapid Lysate Prep Kit (50 filters)
The BlastR™ filters allows for fast and reliable preparation of genomic DNA (gDNA)-free cell lysate for western blot or immunoprecipitation when used in combination with a denaturing buffer, such as guanidine, urea or high SDS based extraction buffers that usually produce copious viscosity. gDNA contamination is a significant problem with denaturing buffers that can interfere with downstream applications like immunoprecipitation and migration of proteins in SDS-PAGE. Unlike sonication or insulin needle gDNA shearing methods, the BlastR™ filter effectively removes gDNA contamination while having no effect on the integrity of the proteins in the lysate.
Cayman Chemical CochlIoquInon A 2.5mg
An inhibitor of DGK (Ki = 3.1 µM) and DGAT (IC50 = 5.6 µM); reduces the concentration of phosphatidic acid in T cell lymphoma (IC50 = 3 µM); binds to human CCR5 chemokine receptors with an IC50 value of 11 µM